Cholesterol and Mevalonate: Two Metabolites Involved in Breast Cancer Progression and Drug Resistance through the ERRα Pathway

Breast cancer is the second greatest cause of cancer-related death in women. Resistance to endocrine treatments or chemotherapy is a limiting drawback. In this context, this work aims to evaluate the effects of cholesterol and mevalonate during tumor progression and their contribution in the onset o...

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Bibliographic Details
Published in:Cells
Main Authors: Matteo Brindisi, Marco Fiorillo, Luca Frattaruolo, Federica Sotgia, Michael P. Lisanti, Anna Rita Cappello
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Subjects:
cholesterol
mevalonate
ERRα
cancer metabolism
CSCs
drug resistance
Online Access:https://www.mdpi.com/2073-4409/9/8/1819

Internet

https://www.mdpi.com/2073-4409/9/8/1819

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