Significance of Five-Membered Heterocycles in Human Histone Deacetylase Inhibitors

Five-membered heteroaromatic rings, in particular, have gained prominence in medicinal chemistry as they offer enhanced metabolic stability, solubility and bioavailability, crucial factors in developing effective drugs. The unique physicochemical properties and biological effects of five-membered he...

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Bibliographic Details

Published in:	Molecules
Main Authors:	Anton Frühauf, Martin Behringer, Franz-Josef Meyer-Almes
Format:	Article
Language:	English
Published:	MDPI AG 2023-07-01
Subjects:	histone deacetylase inhibitors drug development drug design active pharmaceutical ingredient active substance optimization
Online Access:	https://www.mdpi.com/1420-3049/28/15/5686