A first-in-class dimethyl 2-acetamido terephthalate inhibitor targeting Conyza canadensis SHMT1 with a novel herbicidal mode-of-action

Introduction: Herbicide application is a highly efficiency method of weed control that boots agricultural output and assures food security. The development of novel herbicides focuses on improved bioactivity and new modes of action. The amino acid biosynthesis was validated as a promising novel mode...

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Bibliographic Details

Published in:	Journal of Advanced Research
Main Authors:	Dingfeng Luo, Zhendong Bai, Haodong Bai, Na Liu, Jincai Han, Changsheng Ma, Di Wu, Lianyang Bai, Zuren Li
Format:	Article
Language:	English
Published:	Elsevier 2024-08-01
Subjects:	Herbicide target Serine hydroxymethyltransferase (SHMT) Crystal structure In silico screening Synthesis
Online Access:	http://www.sciencedirect.com/science/article/pii/S2090123223002953