Exosomes: The Link Between GPCR Activation and Metastatic Potential?

The activation of G-Protein Coupled Receptors (GPCRs) by their respective ligands initiates a cascade of multiple signaling processes within the cell, regulating growth, metabolism and other essential cellular functions. Dysregulation and aberrant expression of these GPCRs and their subsequent signa...

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Bibliographic Details

Published in:	Frontiers in Genetics
Main Authors:	Allison Leigh Isola, Suzie eChen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2016-04-01
Subjects:	Cancer GPCR exosome mGluR Pre-metastatic niche
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00056/full