Immune Modulation in the Treatment of Amyotrophic Lateral Sclerosis: A Review of Clinical Trials

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by the degeneration of motor neurons. Though many molecular and genetic causes are thought to serve as predisposing or disease propagating factors, the underlying pathogenesis of the disease is not known. Re...

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Bibliographic Details

Published in:	Frontiers in Neurology
Main Authors:	Syed I. Khalid, Leonel Ampie, Ryan Kelly, Shafeeq S. Ladha, Christopher Dardis
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-09-01
Subjects:	amyotrophic lateral sclerosis immunotherapy microglial activation neuroinflammation SOD1
Online Access:	http://journal.frontiersin.org/article/10.3389/fneur.2017.00486/full