Diosmin Mitigates Gentamicin-Induced Nephrotoxicity in Rats: Insights on miR-21 and -155 Expression, Nrf2/HO-1 and p38-MAPK/NF-κB Pathways

Gentamicin (GNT) is the most frequently used aminoglycoside. However, its therapeutic efficacy is limited due to nephrotoxicity. Thus, the potential anticipatory effect of Diosmin (DIOS) against GNT-prompted kidney damage in rats together with the putative nephroprotective pathways were scrutinized....

وصف كامل

التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Toxics
المؤلفون الرئيسيون:	Rania I. Nadeem, Amany S. Aboutaleb, Nancy S. Younis, Hebatalla I. Ahmed
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	MDPI AG 2023-01-01
الموضوعات:	diosmin gentamicin nephrotoxicity miR-21 miR-155 p38-MAPK
الوصول للمادة أونلاين:	https://www.mdpi.com/2305-6304/11/1/48