Comparison of PDE-5 inhibitors used in erectile dysfunction with some candidate molecules: A study involving molecular docking, ADMET, DFT, biological target, and activity

Abstract Erectile dysfunction (ED) is a urological condition defined as the inability of a man to achieve or maintain an erection. This condition negatively affects his sexual performance and the performance of his partner. Phosphodiesterase type 5 (PDE5) inhibitors are commonly used to treat ED. Ar...

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出版年:	BMC Urology
主要な著者:	Süleyman Sağır, Velid Unsal, Erkan Oner, Reşit Yıldız, Başak Doğru Mert
フォーマット:	論文
言語:	英語
出版事項:	BMC 2025-03-01
主題:	Erectile dysfunction PDE-5 inhibitors NOS Arginase II ADMET Molecular docking
オンライン･アクセス:	https://doi.org/10.1186/s12894-025-01727-5