High genomic stability of Andes virus following successive passage in vivo in Syrian hamsters

ABSTRACT Andes virus (ANDV) is a South American hantavirus that causes hantavirus cardiopulmonary syndrome (HCPS), a severe respiratory infection with a case fatality rate as high as 40%. A critical model for studying HCPS is the Syrian hamster model, which faithfully recapitulates key aspects of th...

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Bibliographic Details

Published in:	Journal of Virology
Main Authors:	Bryce M. Warner, Jérémie Prévost, Nikesh Tailor, Yvon Deschambault, Angela Sloan, Julina Allarie, Levi Klassen, Kathy Frost, Stephanie Booth, Jonathan Audet, Geoff Soule, David Safronetz
Format:	Article
Language:	English
Published:	American Society for Microbiology 2025-08-01
Subjects:	orthohantavirus hantavirus hantavirus pulmonary syndrome Andes virus disease modeling virulence
Online Access:	https://journals.asm.org/doi/10.1128/jvi.00512-25