Endothelial Cell Cystathionine γ‐Lyase Expression Level Modulates Exercise Capacity, Vascular Function, and Myocardial Ischemia Reperfusion Injury

Background Hydrogen sulfide (H2S) is an important endogenous physiological signaling molecule and exerts protective properties in the cardiovascular system. Cystathionine γ‐lyase (CSE), 1 of 3 H2S producing enzyme, is predominantly localized in the vascular endothelium. However, the regulation of CS...

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Bibliographic Details

Published in:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Main Authors:	Huijing Xia, Zhen Li, Thomas E. Sharp, David J. Polhemus, Jean Carnal, Karl H. Moles, Ya‐Xiong Tao, John Elrod, Josef Pfeilschifter, Karl‐Friedrich Beck, David J. Lefer
Format:	Article
Language:	English
Published:	Wiley 2020-10-01
Subjects:	cardioprotection cystathionine γ‐lyase endothelial function hydrogen sulfide nitric oxide
Online Access:	https://www.ahajournals.org/doi/10.1161/JAHA.120.017544