Impact of Perioperative Dexamethasone Administration on Infection and Implant Osseointegration in a Preclinical Model of Orthopedic Device-Related Infection

Glucocorticoids may be given prior to major orthopedic surgery to decrease postoperative nausea, vomiting, and pain. Additionally, many orthopedic patients may be on chronic glucocorticoid therapy. The aim of our study was to investigate whether glucocorticoid administration influences Orthopedic-De...

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Bibliographic Details

Published in:	Microorganisms
Main Authors:	Marc-Antoine Burch, Aron Keshishian, Charlotte Wittmann, Dirk Nehrbass, Keith Thompson, Daniel Arens, R. Geoff Richards, Vuysa Mdingi, Marco Chitto, Mario Morgenstern, T. Fintan Moriarty, Henk Eijer
Format:	Article
Language:	English
Published:	MDPI AG 2024-06-01
Subjects:	<i>Staphylococcus epidermidis</i> periprosthetic joint infection PJI fracture-related infection FRI orthopedic-device-related infection
Online Access:	https://www.mdpi.com/2076-2607/12/6/1134