Early diagnostic BioMARKers in exacerbations of chronic obstructive pulmonary disease: protocol of the exploratory, prospective, longitudinal, single-centre, observational MARKED study

Introduction Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) play a pivotal role in the burden and progressive course of chronic obstructive pulmonary disease (COPD). As such, disease management is predominantly based on the prevention of these episodes of acute worsening of re...

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Bibliographic Details

Published in:	BMJ Open
Main Authors:	Antonio DiGiandomenico, Martijn A Spruit, Frits M E Franssen, Sami O Simons, Sander van Kuijk, Kristoffer Ostridge, Kiki Waeijen-Smit, Jessica Bonnell, Ulf Gehrmann, Bret R Sellman, Tara Kenny, Daphne Peerlings, Sarah Houben-Wilke
Format:	Article
Language:	English
Published:	BMJ Publishing Group 2023-03-01
Online Access:	https://bmjopen.bmj.com/content/13/3/e068787.full