ZDHHC20 mediated S-palmitoylation of fatty acid synthase (FASN) promotes hepatocarcinogenesis

Abstract Background Protein palmitoylation is a reversible fatty acyl modification that undertakes important functions in multiple physiological processes. Dysregulated palmitoylations are frequently associated with the formation of cancer. How palmitoyltransferases for S-palmitoylation are involved...

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Bibliographic Details

Published in:	Molecular Cancer
Main Authors:	Yaqi Mo, Yamei Han, Yang Chen, Chunling Fu, Qing Li, Zhuang Liu, Mingming Xiao, Bo Xu
Format:	Article
Language:	English
Published:	BMC 2024-12-01
Subjects:	Hepatocarcinogenesis S-palmitoylation ZDHHC20 FASN
Online Access:	https://doi.org/10.1186/s12943-024-02195-5