Autologous serum supplementation promotes the phenotype maintenance of human chondrocytes with increased cellular autophagy

Abstract Articular cartilage lacks the capacity for self-repair after injury, rendering autologous chondrocyte transplantation a crucial treatment option for severe cartilage damage. However, the in vitro expansion of chondrocytes in elderly patients poses challenges, particularly due to inadequate...

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Bibliographic Details
Published in:Scientific Reports
Main Authors: Wei Yin, Zhigang Qian, Chun Liu, Baishan Song, Qicai Sun
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
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Online Access:https://doi.org/10.1038/s41598-025-92071-z