Differential regulation of MMP activity by TGFβ1 in fast- and slow- twitch muscle repair: insights from EDL and soleus muscle-derived myoblasts

IntroductionSkeletal muscles are characterized by a significant ability to regenerate in response to injury. However, muscle repair is often inefficient and hindered by the development of fibrosis. The course of muscle repair is related to the type of skeletal muscle, i.e., fast- versus slow-twitch,...

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Bibliographic Details

Published in:	Frontiers in Cell and Developmental Biology
Main Authors:	Paulina Kasprzycka, Maria Anna Ciemerych, Malgorzata Zimowska
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Subjects:	TGFβ1 matrix metalloproteinases MMP-2 and MMP-9 skeletal muscle satellite cells
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2025.1592512/full