A Statistical Journey through the Topological Determinants of the β2 Adrenergic Receptor Dynamics

Activation of G-protein-coupled receptors (GPCRs) is mediated by molecular switches throughout the transmembrane region of the receptor. In this work, we continued along the path of a previous computational study wherein energy transport in the β2 Adrenergic Receptor (β2-AR) was examined and alloste...

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Bibliographic Details

Published in:	Entropy
Main Authors:	Luisa Di Paola, Humanath Poudel, Mauro Parise, Alessandro Giuliani, David M. Leitner
Format:	Article
Language:	English
Published:	MDPI AG 2022-07-01
Subjects:	GPCRs β2 adrenergic receptor allosteric switch Protein Contact Networks dynamical cross-correlation matrix Multivariate Statistical Analysis
Online Access:	https://www.mdpi.com/1099-4300/24/7/998