Vulnerability of invasive glioblastoma cells to lysosomal membrane destabilization

Abstract The current clinical care of glioblastomas leaves behind invasive, radio‐ and chemo‐resistant cells. We recently identified mammary‐derived growth inhibitor (MDGI/FABP3) as a biomarker for invasive gliomas. Here, we demonstrate a novel function for MDGI in the maintenance of lysosomal membr...

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Bibliographic Details

Published in:	EMBO Molecular Medicine
Main Authors:	Vadim Le Joncour, Pauliina Filppu, Maija Hyvönen, Minna Holopainen, S Pauliina Turunen, Harri Sihto, Isabel Burghardt, Heikki Joensuu, Olli Tynninen, Juha Jääskeläinen, Michael Weller, Kaisa Lehti, Reijo Käkelä, Pirjo Laakkonen
Format:	Article
Language:	English
Published:	Springer Nature 2019-05-01
Subjects:	antihistamine glioma LMP MDGI PUFA
Online Access:	https://doi.org/10.15252/emmm.201809034