Subcellular localization of the mouse PRAMEL1 and PRAMEX1 reveals multifaceted roles in the nucleus and cytoplasm of germ cells during spermatogenesis

Abstract Background Preferentially expressed antigen in melanoma (PRAME) is a cancer/testis antigen (CTA) that is predominantly expressed in normal gametogenic tissues and a variety of tumors. Members of the PRAME gene family encode leucine-rich repeat (LRR) proteins that provide a versatile structu...

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Bibliographic Details
Published in:Cell & Bioscience
Main Authors: Wan-Sheng Liu, Chen Lu, Bhavesh V. Mistry
Format: Article
Language:English
Published: BMC 2021-06-01
Subjects:
PRAMEL1
PRAMEX1
Cancer-testis antigen
Immunoelectron microscopy
Germ granule
Chromatoid body
Online Access:https://doi.org/10.1186/s13578-021-00612-6

Internet

https://doi.org/10.1186/s13578-021-00612-6

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