Understanding laterality disorders and the left-right organizer: Insights from zebrafish

Vital internal organs display a left-right (LR) asymmetric arrangement that is established during embryonic development. Disruption of this LR asymmetry—or laterality—can result in congenital organ malformations. Situs inversus totalis (SIT) is a complete concordant reversal of internal organs that...

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Bibliographic Details

Published in:	Frontiers in Cell and Developmental Biology
Main Authors:	Kadeen Forrest, Alexandria C. Barricella, Sonny A. Pohar, Anna Maria Hinman, Jeffrey D. Amack
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-12-01
Subjects:	organ laterality left-right asymmetry birth defects zebrafish cilia situs inversus
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2022.1035513/full