SUMO1 modification of KHSRP regulates tumorigenesis by preventing the TL-G-Rich miRNA biogenesis

Abstract Background MicroRNAs (miRNAs) are important regulators involved in diverse physiological and pathological processes including cancer. SUMO (small ubiquitin-like modifier) is a reversible protein modifier. We recently found that SUMOylation of TARBP2 and DGCR8 is involved in the regulation o...

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Bibliographic Details

Published in:	Molecular Cancer
Main Authors:	Haihua Yuan, Rong Deng, Xian Zhao, Ran Chen, Guofang Hou, Hailong Zhang, Yanli Wang, Ming Xu, Bin Jiang, Jianxiu Yu
Format:	Article
Language:	English
Published:	BMC 2017-10-01
Subjects:	KHSRP SUMO1 modification TL-G-Rich miRNA biogenesis Tumorgenesis
Online Access:	http://link.springer.com/article/10.1186/s12943-017-0724-6