Safety and efficacy of trifluridine/tipiracil in previously treated metastatic colorectal cancer: final results from the phase IIIb single-arm PRECONNECT study by duration of therapy

Abstract Background PRECONNECT was an international, phase IIIb trial evaluating the safety and efficacy of trifluridine/tipiracil (FTD/TPI) for metastatic colorectal cancer (mCRC). Methods Patients with mCRC received FTD/TPI 35 mg/m2 twice-daily on days 1–5 and 8–12 of each 28-day cycle for third-...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Julien Taieb, Timothy Price, Loïck Vidot, Bénédicte Chevallier, Lucjan Wyrwicz, Jean-Baptiste Bachet
Format: Article
Language:English
Published: BMC 2023-01-01
Online Access:https://doi.org/10.1186/s12885-022-10489-4