Reverse GWAS: Using genetics to identify and model phenotypic subtypes.

Recent and classical work has revealed biologically and medically significant subtypes in complex diseases and traits. However, relevant subtypes are often unknown, unmeasured, or actively debated, making automated statistical approaches to subtype definition valuable. We propose reverse GWAS (RGWAS...

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Bibliographic Details

Published in:	PLoS Genetics
Main Authors:	Andy Dahl, Na Cai, Arthur Ko, Markku Laakso, Päivi Pajukanta, Jonathan Flint, Noah Zaitlen
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2019-04-01
Online Access:	https://doi.org/10.1371/journal.pgen.1008009