Mechanistic Sequence of Histone Deacetylase Inhibitors and Radiation Treatment: An Overview

Histone deacetylases inhibitors (HDACis) have shown promising therapeutic outcomes in haematological malignancies such as leukaemia, multiple myeloma, and lymphoma, with disappointing results in solid tumours when used as monotherapy. As a result, combination therapies either with radiation or other...

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Bibliographic Details

Published in:	Pharmaceuticals
Main Authors:	Elsie Neo Seane, Shankari Nair, Charlot Vandevoorde, Anna Joubert
Format:	Article
Language:	English
Published:	MDPI AG 2024-05-01
Subjects:	histone deacetylase inhibitors radiosensitisation heterochromatin double strand break DNA repair
Online Access:	https://www.mdpi.com/1424-8247/17/5/602