Exploring the potential mediating role of systemic antibiotics in the association between early-life lower respiratory tract infections and asthma at age 5 in the CHILD study

ObjectiveLower respiratory tract infections (LRTIs) in early life are one of the strongest risk factors for childhood asthma and are often treated with systemic antibiotics (IV or oral). We aimed to explore the association between early-life LRTIs and systemic antibiotics on asthma development and t...

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Bibliographic Details

Published in:	Frontiers in Allergy
Main Authors:	Maria V. Medeleanu, Myrtha E. Reyna, Darlene L. Y. Dai, Geoffrey L. Winsor, Fiona S. L. Brinkman, Rahul Verma, Ella Nugent, Nashita Riaz, Elinor Simons, Piushkumar J. Mandhane, Meghan B. Azad, Stuart E. Turvey, Theo J. Moraes, Padmaja Subbarao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Subjects:	preschool asthma respiratory tract infections antibiotics mediation analyses cohort study clinical epidemiology
Online Access:	https://www.frontiersin.org/articles/10.3389/falgy.2024.1463867/full