Sleep pattern and learning in knockdown mice with reduced cholinergic neurotransmission

Impaired cholinergic neurotransmission can affect memory formation and influence sleep-wake cycles (SWC). In the present study, we describe the SWC in mice with a deficient vesicular acetylcholine transporter (VAChT) system, previously characterized as presenting reduced acetylcholine release and co...

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Bibliographic Details

Published in:	Brazilian Journal of Medical and Biological Research
Main Authors:	C.M. Queiroz, P.A. Tiba, K.M. Moreira, P.A.M. Guidine, G.H.S. Rezende, M.F.D. Moraes, M.A.M. Prado, V.F. Prado, S. Tufik, L.E. Mello
Format:	Article
Language:	English
Published:	Associação Brasileira de Divulgação Científica 2013-01-01
Subjects:	Sleep-wake cycle Intermediate sleep Acetylcholine Contextual fear conditioning Memory Neurodegenerative disorders
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013001000844&lng=en&tlng=en