Mixed effects models but not t-tests or linear regression detect progression of apathy in Parkinson’s disease over seven years in a cohort: a comparative analysis

Abstract Introduction While there is an interest in defining longitudinal change in people with chronic illness like Parkinson’s disease (PD), statistical analysis of longitudinal data is not straightforward for clinical researchers. Here, we aim to demonstrate how the choice of statistical method m...

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Bibliographic Details

Published in:	BMC Medical Research Methodology
Main Authors:	Anne-Marie Hanff, Rejko Krüger, Christopher McCrum, Christophe Ley, NCER-PD
Format:	Article
Language:	English
Published:	BMC 2024-08-01
Subjects:	Cohort studies Epidemiology Disease progression Parkinson Lost to follow-up Statistical model
Online Access:	https://doi.org/10.1186/s12874-024-02301-7