Cholesteryl hemiazelate identified in CVD patients causes in vitro and in vivo inflammation

Oxidation of PUFAs in LDLs trapped in the arterial intima plays a critical role in atherosclerosis. Though there have been many studies on the atherogenicity of oxidized derivatives of PUFA-esters of cholesterol, the effects of cholesteryl hemiesters (ChEs), the oxidation end products of these ester...

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发表在:	Journal of Lipid Research
Main Authors:	Neuza Domingues, Joana Gaifem, Rune Matthiesen, Diana P. Saraiva, Luís Bento, André R.A. Marques, Maria I.L. Soares, Julio Sampaio, Christian Klose, Michal A. Surma, Manuel S. Almeida, Gustavo Rodrigues, Pedro Araújo Gonçalves, Jorge Ferreira, Ryan Gouveia e Melo, Luís Mendes Pedro, Kai Simons, Teresa M.V.D. Pinho e Melo, M. Guadalupe Cabral, Antonio Jacinto, Ricardo Silvestre, Winchil Vaz, Otília V. Vieira
格式:	文件
语言:	英语
出版:	Elsevier 2023-09-01
主题:	cholesteryl hemiesters cholesteryl hemiazelates lipidomics innate inflammatory responses atherosclerosis
在线阅读:	http://www.sciencedirect.com/science/article/pii/S0022227523000925