Association of PD-L1 and PD-L2 expression and tumor-infiltrating lymphocytes in BRAF V600E-mutated metastatic colorectal cancer: GI-SCREEN post-hoc analysis

Background: The programmed cell death protein 1 (PD-1)/programmed cell death-ligand 1 (PD-L1)/programmed cell death-ligand 2 (PD-L2) axis is responsible for cancer immune escape, which facilitates disease progression. However, the role of PD-L1 and PD-L2 and tumor-infiltrating lymphocytes (TILs) in...

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Bibliographic Details

Published in:	ESMO Gastrointestinal Oncology
Main Authors:	M. Imai, Y. Nakamura, T. Denda, Y. Komatsu, S. Yuki, T. Nishina, Y. Hamamoto, H. Hara, T. Esaki, H. Kawakami, K. Kato, T. Satoh, N. Okano, Y. Sunakawa, H. Taniguchi, K. Yamaguchi, T. Yamada, I. Miki, M. Wakabayashi, T. Kuwata, K. Shitara, T. Yoshino
Format:	Article
Language:	English
Published:	Elsevier 2023-12-01
Subjects:	metastatic colorectal cancer PD-L1 PD-L2 TIL BRAF V600E overall survival
Online Access:	http://www.sciencedirect.com/science/article/pii/S2949819823000079