High prevalence of colistin heteroresistance in specific species and lineages of Enterobacter cloacae complex derived from human clinical specimens

Abstract Background Colistin (CST) is a last-line drug for multidrug-resistant Gram-negative bacterial infections. CST-heteroresistant Enterobacter cloacae complex (ECC) has been isolated. However, integrated analysis of epidemiology and resistance mechanisms based on the complete ECC species identi...

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Bibliographic Details

Published in:	Annals of Clinical Microbiology and Antimicrobials
Main Authors:	Shota Fukuzawa, Toyotaka Sato, Kotaro Aoki, Soh Yamamoto, Noriko Ogasawara, Chie Nakajima, Yasuhiko Suzuki, Motohiro Horiuchi, Satoshi Takahashi, Shin-ichi Yokota
Format:	Article
Language:	English
Published:	BMC 2023-07-01
Subjects:	Enterobacter cloacae complex Colistin Heteroresistance arnT PhoPQ Average nucleotide identity (ANI)
Online Access:	https://doi.org/10.1186/s12941-023-00610-1