Embryonic Origin and Subclonal Evolution of Tumor-Associated Macrophages Imply Preventive Care for Cancer

Macrophages are widely distributed in tissues and function in homeostasis. During cancer development, tumor-associated macrophages (TAMs) dominatingly support disease progression and resistance to therapy by promoting tumor proliferation, angiogenesis, metastasis, and immunosuppression, thereby maki...

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Bibliographic Details
Published in:Cells
Main Authors: Xiao-Mei Zhang, De-Gao Chen, Shengwen Calvin Li, Bo Zhu, Zhong-Jun Li
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Subjects:
tumor-associated macrophages (TAMs)
heterogeneity
origins
subclonal evolution
metabolism
cancer target therapy
Online Access:https://www.mdpi.com/2073-4409/10/4/903

Internet

https://www.mdpi.com/2073-4409/10/4/903

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