Validation of computational fluid dynamics of shake flask experiments at moderate viscosity by liquid distributions and volumetric power inputs

Abstract Computational fluid dynamics (CFD) has recently become a pivotal tool in the design and scale-up of bioprocesses. While CFD has been extensively utilized for stirred tank reactors (STRs), there exists a relatively limited body of literature focusing on CFD applications for shake flasks, alm...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Carl Dinter, Andreas Gumprecht, Matthias Alexander Menze, Amizon Azizan, Paul-Joachim Niehoff, Sven Hansen, Jochen Büchs
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-02-01
Online Access:	https://doi.org/10.1038/s41598-024-53980-7