Microglia and amyloid precursor protein coordinate control of transient Candida cerebritis with memory deficits

The potential links between infections and neurodegenerative disorders are unclear. Here, Wu et al. present a mouse model of low-grade candidemia characterized by highly localized cerebritis, accumulation of amyloid precursor protein and beta peptides, and mild memory impairment that resolves with f...

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Bibliographic Details

Published in:	Nature Communications
Main Authors:	Yifan Wu, Shuqi Du, Jennifer L. Johnson, Hui-Ying Tung, Cameron T. Landers, Yuwei Liu, Brittany G. Seman, Robert T. Wheeler, Mauro Costa-Mattioli, Farrah Kheradmand, Hui Zheng, David B. Corry
Format:	Article
Language:	English
Published:	Nature Portfolio 2019-01-01
Online Access:	https://doi.org/10.1038/s41467-018-07991-4