Generation of a TRPV1 knockout human pluripotent stem cell line (WAe009-A-U) using CRISPR/Cas9

The transient receptor potential vanilloid subfamily 1 (TRPV1) is a polymodal nociceptor that is highly expressed in sensory nerves. Activation of TRPV1 receptors excites primary afferent nociceptors by opening cation channels, allowing the influx of Na+ and Ca2+ ions into the cytoplasm. Here, a TRP...

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Bibliographic Details

Published in:	Stem Cell Research
Main Authors:	Yuhong Cao, Ling Tang, Jun Su, Hao Wang, Ping Liang, Kuang Rong, Tingyu Gong
Format:	Article
Language:	English
Published:	Elsevier 2023-10-01
Online Access:	http://www.sciencedirect.com/science/article/pii/S1873506123001885