Alcohol induced hepatic retinoid depletion is associated with the induction of multiple retinoid catabolizing cytochrome P450 enzymes.

Chronic alcohol consumption leads to a spectrum of liver disease that is associated with significant global mortality and morbidity. Alcohol is known to deplete hepatic vitamin A content, which has been linked to the pathogenesis of alcoholic liver disease. It has been suggested that induction of Cy...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Afroza Ferdouse, Rishi R Agrawal, Madeleine A Gao, Hongfeng Jiang, William S Blaner, Robin D Clugston
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2022-01-01
Online Access:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0261675&type=printable