Alcohol induced hepatic retinoid depletion is associated with the induction of multiple retinoid catabolizing cytochrome P450 enzymes.
Chronic alcohol consumption leads to a spectrum of liver disease that is associated with significant global mortality and morbidity. Alcohol is known to deplete hepatic vitamin A content, which has been linked to the pathogenesis of alcoholic liver disease. It has been suggested that induction of Cy...
| Published in: | PLoS ONE |
|---|---|
| Main Authors: | Afroza Ferdouse, Rishi R Agrawal, Madeleine A Gao, Hongfeng Jiang, William S Blaner, Robin D Clugston |
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2022-01-01
|
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0261675&type=printable |
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