Glycan Profiling in Small Extracellular Vesicles with a SERS Microfluidic Biosensor Identifies Early Malignant Development in Lung Cancer

Abstract Glycosylation is the most common post‐translational modification of proteins and regulates a myriad of fundamental biological processes under normal, and pathological conditions. Altered protein glycosylation is linked to malignant transformation, showing distinct glycopatterns that are ass...

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Bibliographic Details

Published in:	Advanced Science
Main Authors:	Quan Zhou, Xueming Niu, Zhen Zhang, Kenneth O'Byrne, Arutha Kulasinghe, David Fielding, Andreas Möller, Alain Wuethrich, Richard J. Lobb, Matt Trau
Format:	Article
Language:	English
Published:	Wiley 2024-09-01
Subjects:	early diagnosis extracellular vesicles glycosylation liquid biopsies miniaturized biosensors non‐small cell lung cancer
Online Access:	https://doi.org/10.1002/advs.202401818