CD8α Structural Domains Enhance GUCY2C CAR-T Cell Efficacy
Despite success in treating some hematological malignancies, CAR-T cells have not yet produced similar outcomes in solid tumors due, in part, to the tumor microenvironment, poor persistence, and a paucity of suitable target antigens. Importantly, the impact of the CAR components on these challenges...
| Published in: | Cancer Biology & Therapy |
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| Main Authors: | , , , , , , |
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2024-12-01
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| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/15384047.2024.2398801 |