LAPTM4B enhances the stemness of CD133+ liver cancer stem-like cells via WNT/β-catenin signaling

Background & Aims: Lysosome-associated protein transmembrane 4β (LAPTM4B) is an oncogene implicated in the malignant progression of hepatocellular carcinoma (HCC). Previous research established a strong association between LAPTM4B and HCC stemness. However, specific mechanisms by which LAPTM...

詳細記述

書誌詳細

出版年:	JHEP Reports
主要な著者:	Jiahong Wang, Jianping Liao, Ye Cheng, Meirong Chen, Aimin Huang
フォーマット:	論文
言語:	英語
出版事項:	Elsevier 2025-04-01
主題:	LAPTM4B β-Catenin stabilization Ubiquitination Deubiquitinating enzymes WNT signaling inhibitors Cancer stem cells
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2589555924003100