Qi-Shen-Tang alleviates retinitis pigmentosa by inhibiting ferroptotic features via the NRF2/GPX4 signaling pathway

Ferroptosis has been observed during retinal photoreceptor cell death, suggesting that it plays a role in retinitis pigmentosa (RP) pathogenesis. Qi-Shen-Tang (QST) is a combination of two traditional Chinese medicines used for the treatment of ophthalmic diseases; however, its mechanism of action i...

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Bibliographic Details

Published in:	Heliyon
Main Authors:	Meng Xiong, Chen Ou, Chang Yu, Jingyue Qiu, Jing Lu, Chaojun Fu, Qinghua Peng, Meiyan Zeng, Houpan Song
Format:	Article
Language:	English
Published:	Elsevier 2023-11-01
Subjects:	Qi-Shen-Tang Retinitis pigmentosa NRF2 GPX4 ferroptosis
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844023096512