Age-related reduction in the functional properties of adult stem cells located in the peripheral region of human retinal pigment epithelium

Purpose: Adult stem cells (SCs) with self-renewal and multilineage potential have been reported upon culturing human retinal pigment epithelial (RPE) cells. The current study aimed to identify the location of SCs in human RPE and to elucidate the age-related changes. Methods: Peripheral, equatorial,...

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Bibliographic Details

Published in:	Indian Journal of Ophthalmology
Main Authors:	Waseema Arif, Siddharth Narendran, Naresh Babu Kannan, Kim Ramasamy, Muthukkaruppan Veerappan, Gowri Priya Chidambaranathan
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2025-04-01
Subjects:	adult stem cells aging clone-forming ability human retinal pigment epithelium label-retaining cell property sphere-forming ability
Online Access:	https://journals.lww.com/10.4103/IJO.IJO_2491_23