A versatile method for multiclass determination of β-lactam drugs in urine by solid-phase extraction followed by HILIC-UV

A method for multiclass determination of β-lactam antibiotics in human urine by solid-phase extraction (SPE) prior to quantification by hydrophilic interaction liquid chromatography (HILIC) was developed. Four cephalosporins, one carbapenem and four penicillins were selected among the most prescribe...

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Bibliographic Details

Published in:	Journal of Chromatography Open
Main Authors:	Francesca Merlo, Jacopo Montagna, Federica Maraschi, Antonella Profumo, Fausto Baldanti, Andrea Speltini
Format:	Article
Language:	English
Published:	Elsevier 2022-11-01
Subjects:	Urine Solid-phase extraction Clean-up β-lactams HILIC Bioanalysis
Online Access:	http://www.sciencedirect.com/science/article/pii/S2772391722000196