Pharmacological SERCA activation limits diet-induced steatohepatitis and restores liver metabolic function in mice

Metabolic dysfunction-associated steatotic liver disease is the most common form of liver disease and poses significant health risks to patients who progress to metabolic dysfunction-associated steatohepatitis. Fatty acid overload alters endoplasmic reticulum (ER) calcium stores and induces mitochon...

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Bibliographic Details

Published in:	Journal of Lipid Research
Main Authors:	Tomasz K. Bednarski, Mohsin Rahim, Clinton M. Hasenour, Deveena R. Banerjee, Irina A. Trenary, David H. Wasserman, Jamey D. Young
Format:	Article
Language:	English
Published:	Elsevier 2024-06-01
Subjects:	hepatology nonalcoholic fatty liver disease metabolic dysfunction-associated steatotic liver disease nonalcoholic steatohepatitis metabolic dysfunction-associated steatohepatitis metabolism
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227524000634