Farnesoid X Receptor Regulated Sepsis‐Induced Abnormal Bile Acid Metabolism via the Fibroblast Growth Factor 15/Fibroblast Growth Factor Receptor 4 Pathway

Abstract Objective The study aims to investigate the mechanism of Farnesoid X receptor (FXR) activation in sepsis‐induced abnormal bile acid metabolism and the metabolism status of each bile acid type. Methods The sepsis mouse model was developed via lipopolysaccharide intraperitoneal injection and...

Full description

Bibliographic Details

Published in:	Immunity, Inflammation and Disease
Main Authors:	Ziyang Zhou, Dan Xu, Liou Huang, Yuhui Cui, Hui Chen, Jianguo Tang
Format:	Article
Language:	English
Published:	Wiley 2025-04-01
Subjects:	bile acid farnesoid X receptor FGF15/FXFR pathway metabolomics sepsis
Online Access:	https://doi.org/10.1002/iid3.70155