The Pharmacokinetics of CPZEN-45, a Novel Anti-Tuberculosis Drug, in Guinea Pigs

CPZEN-45 is a novel compound with activity against drug-susceptible and drug-resistant tuberculosis (TB). The present study was undertaken to determine the best dose and dosing regimen of inhalable CPZEN-45 powders to use in efficacy studies with TB-infected guinea pigs. The disposition of CPZEN-45...

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Bibliographic Details

Published in:	Pharmaceutics
Main Authors:	Lucila Garcia-Contreras, Shumaila Nida Muhammad Hanif, Mariam Ibrahim, Phillip Durham, Anthony J. Hickey
Format:	Article
Language:	English
Published:	MDPI AG 2023-12-01
Subjects:	tuberculosis insufflation passive inhalation pharmacokinetics studies CPZEN-45 guinea pigs
Online Access:	https://www.mdpi.com/1999-4923/15/12/2758