Variation in targetable genomic alterations in non-small cell lung cancer by genetic ancestry, sex, smoking history, and histology

Abstract Background Genomic alterations in 8 genes are now the targets of FDA-approved therapeutics in non-small cell lung cancer (NSCLC), but their distribution according to genetic ancestry, sex, histology, and smoking is not well established. Methods Using multi-institutional genetic testing data...

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發表在:	Genome Medicine
Main Authors:	Elio Adib, Amin H. Nassar, Sarah Abou Alaiwi, Stefan Groha, Elie W. Akl, Lynette M. Sholl, Kesi S. Michael, Mark M. Awad, Pasi A. Jӓnne, Alexander Gusev, David J. Kwiatkowski
格式:	Article
語言:	英语
出版:	BMC 2022-04-01
主題:	Non-small cell lung cancer Targeted therapies Targetable genomic alterations Genetic ancestry Smoking
在線閱讀:	https://doi.org/10.1186/s13073-022-01041-x