Seminal plasma cfDNA fragmentomics landscape delineates male infertility subtypes

Abstract Background While cell-free DNA (cfDNA) fragmentomics has transformed liquid biopsy applications in prenatal screening and oncology, its potential in male reproductive health remains unexplored. Methods Through integrated whole-genome sequencing and jagged end sequencing (Jag-Seq) coupled wi...

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發表在:	Clinical Epigenetics
Main Authors:	Xiaoyu Wu, Fan Meng, Huiping Zhang, Zeqing Li, Kai Zhao
格式:	Article
語言:	英语
出版:	BMC 2025-10-01
主題:	Cell-free DNA Male infertility Fragmentomics
在線閱讀:	https://doi.org/10.1186/s13148-025-01973-2