GRAF1 Acts as a Downstream Mediator of Parkin to Regulate Mitophagy in Cardiomyocytes

Cardiomyocytes rely on proper mitochondrial homeostasis to maintain contractility and achieve optimal cardiac performance. Mitochondrial homeostasis is controlled by mitochondrial fission, fusion, and mitochondrial autophagy (mitophagy). Mitophagy plays a particularly important role in promoting the...

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Bibliographic Details

Published in:	Cells
Main Authors:	Qiang Zhu, Matthew E. Combs, Dawn E. Bowles, Ryan T. Gross, Michelle Mendiola Pla, Christopher P. Mack, Joan M. Taylor
Format:	Article
Language:	English
Published:	MDPI AG 2024-03-01
Subjects:	GRAF1 PINK1-Parkin pathway mitophagy cardiomyocytes metabolism
Online Access:	https://www.mdpi.com/2073-4409/13/5/448