Arsenic Trioxide Decreases Lymphangiogenesis by Inducing Apoptotic Pathways and Inhibition of Important Endothelial Cell Receptors

Tumor-induced lymphangiogenesis is strongly associated with the formation of tumor metastasis. Therefore, the regulation of lymphangiogenesis offers a promising target in cancer therapy. Arsenic trioxide (ATO) is highly effective in the treatment of patients with acute promyelocytic leukemia (APL)....

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Bibliographic Details

Published in:	Current Issues in Molecular Biology
Main Authors:	Igor Hrgovic, Eva Zöller, Monika Doll, Tsige Hailemariam-Jahn, Thilo Jakob, Roland Kaufmann, Markus Meissner, Johannes Kleemann
Format:	Article
Language:	English
Published:	MDPI AG 2023-12-01
Subjects:	arsenic trioxide (ATO) lymphangiogenesis apoptotic pathways Tie-2 VEGFR-2/3 Lyve-1
Online Access:	https://www.mdpi.com/1467-3045/46/1/6