Impaired Expression of Cytoplasmic Actins Leads to Chromosomal Instability of MDA-MB-231 Basal-Like Mammary Gland Cancer Cell Line

We have shown previously that two cytoplasmic actin isoforms play different roles in neoplastic cell transformation. Namely, β-cytoplasmic actin acts as a tumor suppressor, whereas γ-cytoplasmic actin enhances malignant features of tumor cells. The distinct participation of each cytoplasmic actin in...

Full description

Bibliographic Details

Published in:	Molecules
Main Authors:	Vera Dugina, Galina Shagieva, Mariya Novikova, Svetlana Lavrushkina, Olga Sokova, Igor Kireev, Pavel Kopnin
Format:	Article
Language:	English
Published:	MDPI AG 2021-04-01
Subjects:	mammary gland cancer actin isoforms chromosomal instability (CIN)
Online Access:	https://www.mdpi.com/1420-3049/26/8/2151