Non-coding variants impact cis-regulatory coordination in a cell type-specific manner

Abstract Background Interactions among cis-regulatory elements (CREs) play a crucial role in gene regulation. Various approaches have been developed to map these interactions genome-wide, including those relying on interindividual epigenomic variation to identify groups of covariable regulatory elem...

Full description

Bibliographic Details

Published in:	Genome Biology
Main Authors:	Olga Pushkarev, Guido van Mierlo, Judith Franziska Kribelbauer, Wouter Saelens, Vincent Gardeux, Bart Deplancke
Format:	Article
Language:	English
Published:	BMC 2024-07-01
Subjects:	Cis-regulatory interactions Epigenomics Genome-wide association studies Quantitative trait loci Gene regulation
Online Access:	https://doi.org/10.1186/s13059-024-03333-4