Novel Naproxen Salts with Increased Skin Permeability

The paper presents the synthesis, full identification, and characterization of new salts-L-proline alkyl ester naproxenates [ProOR][NAP], where R was a chain from ethyl to butyl (including isopropyl). All obtained compounds were characterized by Nuclear Magnetic Resonance (NMR), Fourier transform in...

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Bibliographic Details
Published in:Pharmaceutics
Main Authors: Ewelina Świątek, Paula Ossowicz-Rupniewska, Ewa Janus, Anna Nowak, Peter Sobolewski, Wiktoria Duchnik, Łukasz Kucharski, Adam Klimowicz
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Subjects:
amino acid
naproxen
ionic liquids
nonsteroidal anti-inflammatory drug
transdermal drug delivery
skin barrier
Online Access:https://www.mdpi.com/1999-4923/13/12/2110

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https://www.mdpi.com/1999-4923/13/12/2110

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